Simulating 500 million years of evolution with a language model

Jul 1 PaperNote BI Comments Word Count: 2.2k(words) Read Count: 8(minutes)

Nature Communications-2024 PLMSearch：Protein language model powers accurate and fast sequence search for remote homology

Jun 25 PaperNote BI Comments Word Count: 1.1k(words) Read Count: 4(minutes)

eLife-2024 Sensitive remote homology search by local alignment of small positional embeddings from protein language models

Jun 13 PaperNote BI Comments Word Count: 659(words) Read Count: 2(minutes)

Bioinformatics-2024 Embedding-based alignment：combining protein language models with dynamic programming alignment to detect structural similarities in the twilight-zone

May 29 PaperNote BI Comments Word Count: 641(words) Read Count: 2(minutes)

Nature Biotechnology-2024 Protein remote homology detection and structural alignment using deep learning

Apr 30 PaperNote BI Comments Word Count: 2.3k(words) Read Count: 8(minutes)

Fast protein structure searching using structure graph embeddings

Apr 27 PaperNote BI Comments Word Count: 826(words) Read Count: 3(minutes)

ICLR-2023 SaProt：Protein Language Modeling with Structure-aware Vocabulary

Apr 4 PaperNote BI, cs.Transformer Comments Word Count: 1.1k(words) Read Count: 3(minutes)

Nature Biotechnology-2023 Fast and accurate protein structure search with FoldseekFast and accurate protein structure search with Foldseek

Feb 12 PaperNote BI Comments Word Count: 2k(words) Read Count: 7(minutes)

ICML-2021 E(n) Equivariant Graph Neural Networks

Feb 5 PaperNote BI, cs.GNN Comments Word Count: 931(words) Read Count: 3(minutes)

ACS Synthetic Biology-2019 Machine Learning Applied to Predicting Microorganism Growth Temperatures and Enzyme Catalytic Optima

Feb 3 PaperNote BI Comments Word Count: 816(words) Read Count: 3(minutes)